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Knee Pain and Injury

  • Platelet Rich Plasma Therapy for Bone on bone knee

    Published on June 12, 2014.

    Bone on bone knees

    Often a patient will ask if Platelet Rich Plasma (PRP) Injections will be effective for their “bone on bone” knee. Then they will ask were is the research on PRP? Many studies have been cited on our website – here are a few more.

    PRP for bone on bone knees

    Preliminary results indicate that the treatment with PRP injections is safe and has the potential to reduce pain and improve knee function and quality of live in younger patients with low degree of articular degeneration.” (1)

    Preliminary findings support the application of  PRP as an effective and safe method in the treatment of the initial stages of knee osteoarthritis… (in the treatment of degenerative lesions of articular cartilage of the knee)”  (2)


    The articular cartilage is the tough tissue that covers the ends of bones. In the knees, lesions or tears are very common. If the lesions go all the way through to the bone it is called a full-thickness lesion.

    PRP as non-surgical alternative

    The typical method of repairing this injury is surgery. However articular cartilage lesions represent one of the major unsolved problems in the orthopaedic surgery. (3)

    Recently researchers in China said PRP, Platelet rich Plasma Therapy can present a successful option.

    “Intra-knee-articular injection of PRP to treat knee articular cartilage degeneration is safe, which can alleviate symptoms of pain and swelling and improve the quality of life of patients,” and recommended further study. (4)

    PRP for the knee deterioration

    The body’s first response to soft tissue injury is to deliver platelets. Packed with growth and healing factors, platelets initiate repair and attract the critical assistance of stem cells. PRP therapy’s natural healing process intensifies the body’s efforts by delivering a higher concentration of platelets.

    To create PRP therapy, a small sample of your blood is drawn (similar to a lab test sample) and placed in a centrifuge that spins the blood at high speeds, separating the platelets from the other components. The concentrated platelet rich plasma (PRP) is then injected into and around the point of injury, jump-starting and significantly strengthening the body’s natural healing signal. Because your own blood is used, there is no risk of a transmissible infection and a very low risk of allergic reaction.

    Relieves pain without the risks of surgery or general anesthesia.

    No hospital stay is required. The procedure is performed safely in a medical office and takes approximately one to two hours. And that’s including preparation and recovery time. In fact, most people return to their jobs or usual activities right after the procedure.

    At long last, long lasting non-surgical pain relief.

    Because the goal of PRP therapy is to resolve pain through healing, it could prove to have lasting results. Initial improvement may be seen within a few weeks, gradually increasing as the healing progresses.

    Research studies and clinical practice have shown PRP therapy to be very effective at relieving pain and returning patients to their normal lives. Both ultrasound and MRI images have shown definitive tissue repair after PRP therapy, confirming the healing process. The need for surgery can also be greatly reduced by treating injured tissues before the damage progresses and the condition is irreversible.

    1. Kon E, Buda R, Filardo G, Di Martino A, Timoncini A, Cenacchi A, Fornasari PM, Giannini S, Marcacci M. Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions. Knee Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):472-9. Epub 2009 Oct 17.

    2. Spaková T, Rosocha J, Lacko M, et al. Treatment of knee joint osteoarthritis with autologous platelet-rich plasma in comparison with hyaluronic acid. Am J Phys Med Rehabil. 2012 May;91(5):411-7

    3. Peretti GM, Pozzi A, Ballis R, Deponti D, Pellacci F. Current surgical options for articular cartilage repair.Acta Neurochir Suppl. 2011;108:213-9.

    4. Li M, Zhang C, Ai Z, Yuan T, Feng Y, Jia W. [Therapeutic effectiveness of intra-knee-articular injection of platelet-rich plasma on knee articular cartilage degeneration]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2011 Oct;25(10):1192-6.

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